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Intermedilysin cytolytic activity depends on heparan sulfates and membrane composition
Cholesterol-dependent cytolysins (CDCs), of which intermedilysin (ILY) is an archetypal member, are a group of pore-forming toxins secreted by a large variety of pathogenic bacteria. These toxins, secreted as soluble monomers, oligomerize upon interaction with cholesterol in the target membrane and...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7906465/ https://www.ncbi.nlm.nih.gov/pubmed/33577603 http://dx.doi.org/10.1371/journal.pgen.1009387 |