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The impact of phenotypic heterogeneity of tumour cells on treatment and relapse dynamics

Intratumour heterogeneity is increasingly recognized as a frequent problem for cancer treatment as it allows for the evolution of resistance against treatment. While cancer genotyping becomes more and more established and allows to determine the genetic heterogeneity, less is known about the phenoty...

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Detalles Bibliográficos
Autores principales: Raatz, Michael, Shah, Saumil, Chitadze, Guranda, Brüggemann, Monika, Traulsen, Arne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7906468/
https://www.ncbi.nlm.nih.gov/pubmed/33577569
http://dx.doi.org/10.1371/journal.pcbi.1008702