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Comprehensive Assessment of Protein and Excipient Stability in Biopharmaceutical Formulations Using (1)H NMR Spectroscopy

[Image: see text] Biopharmaceutical proteins are important drug therapies in the treatment of a range of diseases. Proteins, such as antibodies (Abs) and peptides, are prone to chemical and physical degradation, particularly at the high concentrations currently sought for subcutaneous injections, an...

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Detalles Bibliográficos
Autores principales: Bramham, Jack E., Podmore, Adrian, Davies, Stephanie A., Golovanov, Alexander P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7906489/
https://www.ncbi.nlm.nih.gov/pubmed/33659867
http://dx.doi.org/10.1021/acsptsci.0c00188