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Comprehensive Assessment of Protein and Excipient Stability in Biopharmaceutical Formulations Using (1)H NMR Spectroscopy
[Image: see text] Biopharmaceutical proteins are important drug therapies in the treatment of a range of diseases. Proteins, such as antibodies (Abs) and peptides, are prone to chemical and physical degradation, particularly at the high concentrations currently sought for subcutaneous injections, an...
Autores principales: | Bramham, Jack E., Podmore, Adrian, Davies, Stephanie A., Golovanov, Alexander P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7906489/ https://www.ncbi.nlm.nih.gov/pubmed/33659867 http://dx.doi.org/10.1021/acsptsci.0c00188 |
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