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Dynamic effects of genetic variation on gene expression revealed following hypoxic stress in cardiomyocytes
One life-threatening outcome of cardiovascular disease is myocardial infarction, where cardiomyocytes are deprived of oxygen. To study inter-individual differences in response to hypoxia, we established an in vitro model of induced pluripotent stem cell-derived cardiomyocytes from 15 individuals. We...
Autores principales: | Ward, Michelle C, Banovich, Nicholas E, Sarkar, Abhishek, Stephens, Matthew, Gilad, Yoav |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7906610/ https://www.ncbi.nlm.nih.gov/pubmed/33554857 http://dx.doi.org/10.7554/eLife.57345 |
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