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Safety and immunogenicity of S-Trimer (SCB-2019), a protein subunit vaccine candidate for COVID-19 in healthy adults: a phase 1, randomised, double-blind, placebo-controlled trial

BACKGROUND: As part of the accelerated development of vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), we report a dose-finding and adjuvant justification study of SCB-2019, a protein subunit vaccine candidate containing a stabilised trimeric form of the spike (S)-prote...

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Detalles Bibliográficos
Autores principales: Richmond, Peter, Hatchuel, Lara, Dong, Min, Ma, Brenda, Hu, Branda, Smolenov, Igor, Li, Ping, Liang, Peng, Han, Htay Htay, Liang, Joshua, Clemens, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7906655/
https://www.ncbi.nlm.nih.gov/pubmed/33524311
http://dx.doi.org/10.1016/S0140-6736(21)00241-5