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Hypoxia-induced PLOD1 overexpression contributes to the malignant phenotype of glioblastoma via NF-κB signaling

Procollagen lysyl hydroxylase 1 (PLOD1) is highly expressed in malignant tumors such as esophageal squamous cell carcinoma, gastric cancer, and colorectal cancer. Bioinformatics analysis revealed that PLOD1 is associated with the progression of GBM, particularly the most malignant mesenchymal subtyp...

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Detalles Bibliográficos
Autores principales: Wang, Zhenlin, Shi, Yuping, Ying, Chenting, Jiang, Yang, Hu, Jiangfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7906902/
https://www.ncbi.nlm.nih.gov/pubmed/33420370
http://dx.doi.org/10.1038/s41388-020-01635-y