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Reduced lipolysis in lipoma phenocopies lipid accumulation in obesity

BACKGROUND: Elucidation of lipid metabolism and accumulation mechanisms is of paramount importance to understanding obesity and unveiling therapeutic targets. In vitro cell models have been extensively used for these purposes, yet, they do not entirely reflect the in vivo setup. Conventional lipomas...

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Detalles Bibliográficos
Autores principales: Le Duc, Diana, Lin, Chen-Ching, Popkova, Yulia, Yang, Zuqin, Akhil, Velluva, Çakir, M. Volkan, Grunewald, Sonja, Simon, Jan-Christoph, Dietz, Andreas, Dannenberger, Dirk, Garten, Antje, Lemke, Johannes R., Schiller, Jürgen, Blüher, Matthias, Nono Nankam, Pamela Arielle, Rolle-Kampczyk, Ulrike, von Bergen, Martin, Kelso, Janet, Schöneberg, Torsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7906903/
https://www.ncbi.nlm.nih.gov/pubmed/33235355
http://dx.doi.org/10.1038/s41366-020-00716-y