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Whole-genome methylation analysis reveals novel epigenetic perturbations of congenital scoliosis

Congenital scoliosis (CS) is a congenital disease caused by malformations of vertebrae. Recent studies demonstrated that DNA modification could contribute to the pathogenesis of disease. This study aims to identify epigenetic perturbations that may contribute to the pathogenesis of CS. Four CS patie...

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Detalles Bibliográficos
Autores principales: Liu, Gang, Zhao, Hengqiang, Yan, Zihui, Zhao, Sen, Niu, Yuchen, Li, Xiaoxin, Wang, Shengru, Yang, Yang, Liu, Sen, Zhang, Terry Jianguo, Wu, Zhihong, Wu, Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907230/
https://www.ncbi.nlm.nih.gov/pubmed/33717649
http://dx.doi.org/10.1016/j.omtn.2021.02.002