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Iohexol plasma clearance simplified by Dried Blood Spot (DBS) sampling to measure renal function in conscious mice

There is no simple method to measure glomerular filtration rate (GFR) in mice, which limits the use of mice in models of renal diseases. We aimed at simplifying the plasma clearance of iohexol in mice, using dried blood spot (DBS) sampling in order to reduce the amount of blood taken for analysis. G...

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Detalles Bibliográficos
Autores principales: Rodríguez-Rodríguez, Ana Elena, Luis-Lima, Sergio, Donate-Correa, Javier, Diaz-Martín, Laura, Arnau, María Rosa, Jiménez-Sosa, Alejandro, Gaspari, Flavio, Ortiz, Alberto, Porrini, Esteban
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907335/
https://www.ncbi.nlm.nih.gov/pubmed/33633207
http://dx.doi.org/10.1038/s41598-021-83934-2