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Elevation in viral entry genes and innate immunity compromise underlying increased infectivity and severity of COVID-19 in cancer patients

Multiple studies have reported a doubling in risk of Coronavirus Disease-2019 (COVID-19) among cancer patients. Here, we examine the potential biological rationale behind this recurrent epidemiological observation. By leveraging large-scale genome-wide transcriptional data of normal and malignant ti...

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Detalles Bibliográficos
Autores principales: Kwan, Jennifer Yin Yee, Lin, Liang-Tzung, Bell, Rachel, Bruce, Jeffrey P., Richardson, Christopher, Pugh, Trevor J., Liu, Fei-Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907391/
https://www.ncbi.nlm.nih.gov/pubmed/33633121
http://dx.doi.org/10.1038/s41598-021-83366-y