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Regulation of peripheral Th/Treg differentiation and suppression of airway inflammation by Nr4a transcription factors

Helper T (Th) and regulatory T (Treg) cell differentiation programs promote the eradication of pathogens, while minimizing adverse immune reactions. Here, we found that Nr4a family of nuclear receptors supports Treg cell induction and represses Th1 and Th2 cell differentiation from naive CD4(+) T ce...

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Detalles Bibliográficos
Autores principales: Sekiya, Takashi, Kagawa, Shizuko, Masaki, Katsunori, Fukunaga, Koichi, Yoshimura, Akihiko, Takaki, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907427/
https://www.ncbi.nlm.nih.gov/pubmed/33665581
http://dx.doi.org/10.1016/j.isci.2021.102166