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Regulation of peripheral Th/Treg differentiation and suppression of airway inflammation by Nr4a transcription factors
Helper T (Th) and regulatory T (Treg) cell differentiation programs promote the eradication of pathogens, while minimizing adverse immune reactions. Here, we found that Nr4a family of nuclear receptors supports Treg cell induction and represses Th1 and Th2 cell differentiation from naive CD4(+) T ce...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907427/ https://www.ncbi.nlm.nih.gov/pubmed/33665581 http://dx.doi.org/10.1016/j.isci.2021.102166 |