Characterization of the Signaling Modalities of Prostaglandin E2 Receptors EP2 and EP4 Reveals Crosstalk and a Role for Microtubules

Prostaglandin E2 (PGE2) is a lipid mediator that modulates the function of myeloid immune cells such as macrophages and dendritic cells (DCs) through the activation of the G protein-coupled receptors EP2 and EP4. While both EP2 and EP4 signaling leads to an elevation of intracellular cyclic adenosin...

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Detalles Bibliográficos
Autores principales: Vleeshouwers, Ward, van den Dries, Koen, de Keijzer, Sandra, Joosten, Ben, Lidke, Diane S., Cambi, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907432/
https://www.ncbi.nlm.nih.gov/pubmed/33643295
http://dx.doi.org/10.3389/fimmu.2020.613286

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907432/
https://www.ncbi.nlm.nih.gov/pubmed/33643295
http://dx.doi.org/10.3389/fimmu.2020.613286

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