Impaired Barrier Function and Immunity in the Colon of Aldo-Keto Reductase 1B8 Deficient Mice

Aldo-keto reductase 1B10 (AKR1B10) is downregulated in human ulcerative colitis (UC) and colorectal cancer, being a potential pathogenic factor of these diseases. Aldo-keto reductase 1B8 (AKR1B8) is the ortholog in mice of human AKR1B10. Targeted AKR1B8 deficiency disrupts homeostasis of epithelial...

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Detalles Bibliográficos
Autores principales: Wang, Xin, Khoshaba, Ramina, Shen, Yi, Cao, Yu, Lin, Minglin, Zhu, Yun, Cao, Zhe, Liao, Duan-Fang, Cao, Deliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907435/
https://www.ncbi.nlm.nih.gov/pubmed/33644071
http://dx.doi.org/10.3389/fcell.2021.632805

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907435/
https://www.ncbi.nlm.nih.gov/pubmed/33644071
http://dx.doi.org/10.3389/fcell.2021.632805

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