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Suppression of ELF4 in ulcerative colitis predisposes host to colorectal cancer
Ulcerative colitis (UC) is a chronic inflammatory bowel disease, characterized by relapsing and remitting colon mucosal inflammation. For patients suffering from UC, a higher risk of colon cancer has been widely recognized. Here, we found that Elf4(−/−) mice developed colon tumors with 3 cycles of d...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907480/ https://www.ncbi.nlm.nih.gov/pubmed/33665583 http://dx.doi.org/10.1016/j.isci.2021.102169 |