iNOS Associates With Poor Survival in Melanoma: A Role for Nitric Oxide in the PI3K-AKT Pathway Stimulation and PTEN S-Nitrosylation

We previously showed that inducible nitric oxide synthase (iNOS) protein expression in melanoma tumor cells is associated with poor patient prognosis. Here, we analyzed the association between iNOS and the oncogenic PI3K-AKT pathway. TCGA data show that iNOS and phospho-Akt Ser473 expression were as...

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Detalles Bibliográficos
Autores principales: Ding, Zhen, Ogata, Dai, Roszik, Jason, Qin, Yong, Kim, Sun-Hee, Tetzlaff, Michael T., Lazar, Alexander J., Davies, Michael A., Ekmekcioglu, Suhendan, Grimm, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907506/
https://www.ncbi.nlm.nih.gov/pubmed/33643925
http://dx.doi.org/10.3389/fonc.2021.631766

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907506/
https://www.ncbi.nlm.nih.gov/pubmed/33643925
http://dx.doi.org/10.3389/fonc.2021.631766

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