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The Role of NLRP3 Inflammasome in Pericarditis: Potential for Therapeutic Approaches

Human samples of patients with chronic pericarditis and appropriate control subjects were stained for the inflammasome components. A mouse model of pericarditis was developed through the intrapericardial injection of zymosan A. Different inflammasome blockers were tested in the mouse model. Patients...

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Detalles Bibliográficos
Autores principales: Mauro, Adolfo G., Bonaventura, Aldo, Vecchié, Alessandra, Mezzaroma, Eleonora, Carbone, Salvatore, Narayan, Pratyush, Potere, Nicola, Cannatà, Antonio, Paolini, John F., Bussani, Rossana, Montecucco, Fabrizio, Sinagra, Gianfranco, Van Tassel, Benjamin W., Abbate, Antonio, Toldo, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907621/
https://www.ncbi.nlm.nih.gov/pubmed/33665514
http://dx.doi.org/10.1016/j.jacbts.2020.11.016