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miR-146a inhibits mitochondrial dysfunction and myocardial infarction by targeting cyclophilin D

Increasing evidence suggests that mitochondrial microRNAs (miRNAs) are implicated in the pathogenesis of cardiovascular diseases; however, their roles in ischemic heart disease remain unclear. Herein, we demonstrate that miR-146a is enriched in the mitochondrial fraction of cardiomyocytes, and its l...

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Detalles Bibliográficos
Autores principales: Su, Qiang, Xu, Yuli, Cai, Ruping, Dai, Rixin, Yang, Xiheng, Liu, Yang, Kong, Binghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907681/
https://www.ncbi.nlm.nih.gov/pubmed/33717647
http://dx.doi.org/10.1016/j.omtn.2021.01.034