Hemistepsin A inhibits T0901317-induced lipogenesis in the liver

Hemistepsin A (HsA) is a guaianolide sesquiterpene lactone that inhibits hepatitis and liver fibrosis. We evaluated the effects of HsA on liver X receptor (LXR)-mediated hepatic lipogenesis in vitro and in vivo. Up to 10 μM, HsA did not affect the viability of HepG2 and Huh7 cells. Pretreatment with...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Jae Kwang, Cho, Il Je, Kim, Eun Ok, Lee, Dae Geon, Jung, Dae Hwa, Ki, Sung Hwan, Ku, Sae Kwang, Kim, Sang Chan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907741/
https://www.ncbi.nlm.nih.gov/pubmed/32843130
http://dx.doi.org/10.5483/BMBRep.2021.54.2.111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907741/
https://www.ncbi.nlm.nih.gov/pubmed/32843130
http://dx.doi.org/10.5483/BMBRep.2021.54.2.111

Ejemplares similares