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Pleckstrin homology domain of phospholipase D2 is a negative regulator of focal adhesion kinase

Phospholipase D2 (PLD2) has been implicated in the tyrosine kinase-mediated signaling pathways, but the regulation events are yet to be identified. Herein, we demonstrate that pleckstrin homology (PH) domain of PLD2 (PLD2-PH) exerts an antitumorigenic effect via the suppression of PLD2 and focal adh...

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Detalles Bibliográficos
Autores principales: Kim, Mi Kyoung, Hwang, Won Chan, Min, Do Sik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907743/
https://www.ncbi.nlm.nih.gov/pubmed/32843133
http://dx.doi.org/10.5483/BMBRep.2021.54.2.154