Deciphering the role of a membrane-targeting domain in assisting endosomal and autophagic membrane localization of a RavZ protein catalytic domain

The bacterial effector protein RavZ from a pathogen can impair autophagy in the host by delipidating the mammalian autophagy-related gene 8 (mATG8)-phosphatidylethanolamine (PE) on autophagic membranes. In RavZ, the membrane-targeting (MT) domain is an essential function. However, the molecular mech...

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Detalles Bibliográficos
Autores principales: Park, Jui-Hee, Lee, Seung-Hwan, Park, Sang-Won, Jun, Yong-Woo, Kim, Kunhyung, Jeon, Pureum, Kim, Myungjin, Lee, Jin-A, Jang, Deok-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907744/
https://www.ncbi.nlm.nih.gov/pubmed/33298241
http://dx.doi.org/10.5483/BMBRep.2021.54.2.190

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907744/
https://www.ncbi.nlm.nih.gov/pubmed/33298241
http://dx.doi.org/10.5483/BMBRep.2021.54.2.190

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