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Deciphering the role of a membrane-targeting domain in assisting endosomal and autophagic membrane localization of a RavZ protein catalytic domain
The bacterial effector protein RavZ from a pathogen can impair autophagy in the host by delipidating the mammalian autophagy-related gene 8 (mATG8)-phosphatidylethanolamine (PE) on autophagic membranes. In RavZ, the membrane-targeting (MT) domain is an essential function. However, the molecular mech...
Autores principales: | Park, Jui-Hee, Lee, Seung-Hwan, Park, Sang-Won, Jun, Yong-Woo, Kim, Kunhyung, Jeon, Pureum, Kim, Myungjin, Lee, Jin-A, Jang, Deok-Jin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907744/ https://www.ncbi.nlm.nih.gov/pubmed/33298241 http://dx.doi.org/10.5483/BMBRep.2021.54.2.190 |
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