miR-21-5p Suppresses Mitophagy to Alleviate Hyperoxia-Induced Acute Lung Injury by Directly Targeting PGAM5

Hyperoxia-induced acute lung injury (HALI) is a severe side effect of refractory hypoxemia treatment, for which no effective therapeutic strategy is available. Here, we found that the lung miR-21-5p level was significantly decreased in the rats subjected to hyperoxia. Further, we presented evidence...

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Detalles Bibliográficos
Autores principales: Liu, Guoyue, Qian, Mingjiang, Chen, Miao, Chen, Tao, Qin, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907750/
https://www.ncbi.nlm.nih.gov/pubmed/33681349
http://dx.doi.org/10.1155/2020/4807254

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907750/
https://www.ncbi.nlm.nih.gov/pubmed/33681349
http://dx.doi.org/10.1155/2020/4807254

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