Selective postnatal excitation of neocortical pyramidal neurons results in distinctive behavioral and circuit deficits in adulthood

In genetic and pharmacological models of neurodevelopmental disorders, and human data, neural activity is altered within the developing neocortical network. This commonality begs the question of whether early enhancement in excitation might be a common driver, across etiologies, of characteristic be...

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Detalles Bibliográficos
Autores principales: Medendorp, William E., Bjorefeldt, Andreas, Crespo, Emmanuel L., Prakash, Mansi, Pal, Akash, Waddell, Madison L., Moore, Christopher I., Hochgeschwender, Ute
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907816/
https://www.ncbi.nlm.nih.gov/pubmed/33665575
http://dx.doi.org/10.1016/j.isci.2021.102157

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907816/
https://www.ncbi.nlm.nih.gov/pubmed/33665575
http://dx.doi.org/10.1016/j.isci.2021.102157

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