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Downregulation of epithelial sodium channel (ENaC) activity in human airway epithelia after low temperature incubation

INTRODUCTION: The incubation of airway epithelia cells at low temperatures is a common in vitro experimental approach used in the field of cystic fibrosis (CF) research to thermo-stabilise F508del-CFTR and increase its functional expression. Given that the airway epithelium includes numerous ion tra...

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Detalles Bibliográficos
Autores principales: Yadav, Sangya, Shaughnessy, Ciaran A, Zeitlin, Pamela L, Bratcher, Preston E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907861/
https://www.ncbi.nlm.nih.gov/pubmed/33622672
http://dx.doi.org/10.1136/bmjresp-2020-000861