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Elevated levels of oxidized nucleosides in individuals with the JAK2V617F mutation from a general population study

It is unknown if the somatic mutations in chronic myeloproliferative neoplasms (MPNs), JAK2V617F and Calreticulin, are associated with oxidative stress, or impaired mitochondrial defense against reactive oxygen species. In the Danish General Suburban Population Study (GESUS), including 116 JAK2V617F...

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Detalles Bibliográficos
Autores principales: Sørensen, Anders L., Hasselbalch, Hans C., Bjørn, Mads Emil, Nielsen, Claus H., Cordua, Sabrina, Skov, Vibe, Kjær, Lasse, Poulsen, Henrik E., Ellervik, Christina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907890/
https://www.ncbi.nlm.nih.gov/pubmed/33621788
http://dx.doi.org/10.1016/j.redox.2021.101895