In situ Generation of Antibiotics using Bioorthogonal “Nanofactories”

Prodrug strategies use chemical modifications to improve the pharmacokinetic properties and therefore therapeutic effects of parent drugs. Traditional prodrug approaches use endogenous enzymes for activation. Bioorthogonal catalysis uses processes that endogenous enzymes cannot access, providing a c...

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Detalles Bibliográficos
Autores principales: Li, Cheng-Hsuan, Huang, Rui, Makabenta, Jessa Marie, Schmidt-Malan, Suzannah, Patel, Robin, Rotello, Vincent M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907933/
https://www.ncbi.nlm.nih.gov/pubmed/33707951
http://dx.doi.org/10.1177/1178636121997121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907933/
https://www.ncbi.nlm.nih.gov/pubmed/33707951
http://dx.doi.org/10.1177/1178636121997121

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