Cargando…

In situ Generation of Antibiotics using Bioorthogonal “Nanofactories”

Prodrug strategies use chemical modifications to improve the pharmacokinetic properties and therefore therapeutic effects of parent drugs. Traditional prodrug approaches use endogenous enzymes for activation. Bioorthogonal catalysis uses processes that endogenous enzymes cannot access, providing a c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Cheng-Hsuan, Huang, Rui, Makabenta, Jessa Marie, Schmidt-Malan, Suzannah, Patel, Robin, Rotello, Vincent M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2021
Materias:	Commentary
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907933/ https://www.ncbi.nlm.nih.gov/pubmed/33707951 http://dx.doi.org/10.1177/1178636121997121

Ejemplares similares

All-natural gelatin-based bioorthogonal catalysts for efficient eradication of bacterial biofilms
por: Nabawy, Ahmed, et al.
Publicado: (2022)

Polymeric Nanoparticles Active against Dual-Species Bacterial Biofilms
por: Makabenta, Jessa Marie V., et al.
Publicado: (2021)

Therapeutic Nanofactories: Biotransporting Biocatalytic Reactors toward Therapeutic Nanofactories (Adv. Sci. 11/2018)
por: Nishimura, Tomoki, et al.
Publicado: (2018)

Enhanced Design of Gold Catalysts for Bioorthogonal Polyzymes
por: Hirschbiegel, Cristina-Maria, et al.
Publicado: (2022)

Biotransporting Biocatalytic Reactors toward Therapeutic Nanofactories
por: Nishimura, Tomoki, et al.
Publicado: (2018)

Biomimetic and bioorthogonal nanozymes for biomedical applications
por: Keum, Changjoon, et al.
Publicado: (2023)

Macrophage-Encapsulated Bioorthogonal Nanozymes for Targeting Cancer Cells
por: Das, Riddha, et al.
Publicado: (2022)

1259. Activity of eravacycline against staphylococci isolated from periprosthetic joint infections
por: Zhuchenko, Georg, et al.
Publicado: (2020)

High efficiency and long-term intracellular activity of an enzymatic nanofactory based on metal-organic frameworks
por: Lian, Xizhen, et al.
Publicado: (2017)

Nanofactory for metabolic and chemodynamic therapy: pro-tumor lactate trapping and anti-tumor ROS transition
por: He, Ruiqing, et al.
Publicado: (2021)

Biological synthesis of fluorescent nanoparticles by cadmium and tellurite resistant Antarctic bacteria: exploring novel natural nanofactories
por: Plaza, D. O., et al.
Publicado: (2016)

Integration of Antimicrobials and Delivery Systems: Synergistic Antibiofilm Activity with Biodegradable Nanoemulsions Incorporating Pseudopyronine Analogs
por: Park, Jungmi, et al.
Publicado: (2023)

Monodispersed AgNPs Synthesized from the Nanofactories of Theobroma cacao (Cocoa) Leaves and Pod Husk and Their Antimicrobial Activity
por: Efavi, Johnson Kwame, et al.
Publicado: (2022)

Bioorthogonal in situ assembly of nanomedicines as drug depots for extracellular drug delivery
por: Cao, Ziyang, et al.
Publicado: (2022)

In Situ Bioorthogonal Conjugation of Delivered Bacteria with Gut Inhabitants for Enhancing Probiotics Colonization
por: Song, Wen-Fang, et al.
Publicado: (2022)

691. Activity of TNP-2092 Against Biofilms Formed by Prosthetic Joint Infection-Associated Staphylococci
por: Fisher, Cody, et al.
Publicado: (2019)

Facile aerobic construction of iron based ferromagnetic nanostructures by a novel microbial nanofactory isolated from tropical freshwater wetlands
por: Jacob, Patricia Jayshree, et al.
Publicado: (2017)

Sustainable microbial cell nanofactory for zinc oxide nanoparticles production by zinc-tolerant probiotic Lactobacillus plantarum strain TA4
por: Mohd Yusof, Hidayat, et al.
Publicado: (2020)

The Future of Bioorthogonal Chemistry
por: Devaraj, Neal K.
Publicado: (2018)

Highly multiplexed single-cell in situ RNA and DNA analysis with bioorthogonal cleavable fluorescent oligonucleotides
por: Mondal, Manas, et al.
Publicado: (2018)

Methyltetrazine as a small live-cell compatible bioorthogonal handle for imaging enzyme activities in situ
por: Torres-García, Diana, et al.
Publicado: (2022)

Oritavancin polymethylmethacrylate (PMMA)—compressive strength testing and in vitro elution
por: Schmidt-Malan, Suzannah M., et al.
Publicado: (2019)

Locally delivered antistaphylococcal lysin exebacase or CF-296 is active in methicillin-resistant Staphylococcus aureus implant-associated osteomyelitis
por: Karau, Melissa, et al.
Publicado: (2022)

A Bioorthogonal Quadricyclane Ligation
por: Sletten, Ellen M., et al.
Publicado: (2011)

Interfacial Bioorthogonal Cross-Linking
por: Zhang, Han, et al.
Publicado: (2014)

712. Activity of Exebacase (CF-301) Against Methicillin-Resistant Staphylococcus aureus (MRSA) Biofilms on Orthopedic Kirschner Wires
por: Karau, Melissa J, et al.
Publicado: (2019)

Two-step conversion of unprotected oligosaccharides to generate bioorthogonal oligosaccharide tool compounds
por: Chambers, Schuyler A., et al.
Publicado: (2020)

Bioorthogonal Cyclization-Mediated In Situ Self-Assembly of Small Molecule Probes for Imaging Caspase Activity in vivo
por: Ye, Deju, et al.
Publicado: (2014)

Deuterium- and Alkyne-Based Bioorthogonal Raman Probes for In Situ Quantitative Metabolic Imaging of Lipids within Plants
por: Law, Simon Sau Yin, et al.
Publicado: (2023)

Cell-specific bioorthogonal tagging of glycoproteins
por: Cioce, Anna, et al.
Publicado: (2022)

Bioorthogonal protein-DNA conjugation methods for force spectroscopy
por: Synakewicz, Marie, et al.
Publicado: (2019)

Recently published papers: predictors, pressors and poietins
por: Ward, Suzannah, et al.
Publicado: (2007)

Probing the Mycobacterial Trehalome with Bioorthogonal Chemistry
por: Swarts, Benjamin M., et al.
Publicado: (2012)

Development of Bioorthogonal Reactions and Their Applications in Bioconjugation
por: Zheng, Mengmeng, et al.
Publicado: (2015)

Bioorthogonal Ligations and Cleavages in Chemical Biology
por: Li, Youshan, et al.
Publicado: (2020)

Nanozymes with bioorthogonal reaction for intelligence nanorobots
por: Sun, Si, et al.
Publicado: (2021)

Recent Advances in Bioorthogonal Ligation and Bioconjugation
por: Zielke, Florian M., et al.
Publicado: (2023)

Single-cell recordings reveal subpopulations that grow and generate resistance at bactericidal concentrations of antibiotics
por: Henriques-Normark, B., et al.
Publicado: (2023)

A fertile future: Fertility preservation special series
por: Mitchell, Rod T, et al.
Publicado: (2022)

Bioorthogonal oxime ligation mediated in vivo cancer targeting
por: Tang, Li, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_dakf68ohcd599d2o7j5simh5fb