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Simulating the effect of cerebral blood flow changes on regional quantification of [(18)F]flutemetamol and [(18)F]florbetaben studies

Global and regional changes in cerebral blood flow (CBF) can result in biased quantitative estimates of amyloid load by PET imaging. Therefore, the current simulation study assessed effects of these changes on amyloid quantification using a reference tissue approach for [(18)F]flutemetamol and [(18)...

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Detalles Bibliográficos
Autores principales: Heeman, Fiona, Yaqub, Maqsood, Lopes Alves, Isadora, Heurling, Kerstin, Bullich, Santiago, Gispert, Juan D, Boellaard, Ronald, Lammertsma, Adriaan A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907983/
https://www.ncbi.nlm.nih.gov/pubmed/32281514
http://dx.doi.org/10.1177/0271678X20918029