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Increased acquired protease inhibitor drug resistance mutations in minor HIV-1 quasispecies from infected patients suspected of failing on national second-line therapy in South Africa

BACKGROUND: HIV-1C has been shown to have a greater risk of virological failure and reduced susceptibility towards boosted protease inhibitors (bPIs), a component of second-line combination antiretroviral therapy (cART) in South Africa. This study entailed an evaluation of HIV-1 drug resistance-asso...

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Detalles Bibliográficos
Autores principales: Obasa, Adetayo Emmanuel, Ambikan, Anoop T., Gupta, Soham, Neogi, Ujjwal, Jacobs, Graeme Brendon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7908688/
https://www.ncbi.nlm.nih.gov/pubmed/33632139
http://dx.doi.org/10.1186/s12879-021-05905-2