A base measure of precision for protein stability predictors: structural sensitivity

BACKGROUND: Prediction of the change in fold stability (ΔΔG) of a protein upon mutation is of major importance to protein engineering and screening of disease-causing variants. Many prediction methods can use 3D structural information to predict ΔΔG. While the performance of these methods has been e...

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Detalles Bibliográficos
Autores principales: Caldararu, Octav, Blundell, Tom L., Kepp, Kasper P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7908712/
https://www.ncbi.nlm.nih.gov/pubmed/33632133
http://dx.doi.org/10.1186/s12859-021-04030-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7908712/
https://www.ncbi.nlm.nih.gov/pubmed/33632133
http://dx.doi.org/10.1186/s12859-021-04030-w

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