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Administration of zoledronic acid alleviates osteoporosis in HIV patients by suppressing osteoclastogenesis via regulating RANKL expression

BACKGROUND: Osteoporosis is a common phenomenon in HIV patients on tenofovir treatment, but its underlying mechanisms remain to be explored. METHODS: Quantitative real-time PCR was performed to analyze the expression of miR-302, miR-101, miR-145 and osteoclast-specific genes in the serum of HIV pati...

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Detalles Bibliográficos
Autores principales: Lin, Wei, Li, Xing-fu, Ren, Dong-cheng, Song, Meng, Duan, Li, Liu, Jin-zhu, Zhan, Zi-rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7908730/
https://www.ncbi.nlm.nih.gov/pubmed/33637048
http://dx.doi.org/10.1186/s10020-021-00276-5