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Distribution of chimeric antigen receptor-modified T cells against CD19 in B-cell malignancies

BACKGROUND: The unprecedented efficacy of chimeric antigen receptor T (CAR-T) cell immunotherapy of CD19(+) B-cell malignancies has opened a new and useful way for the treatment of malignant tumors. Nonetheless, there are still formidable challenges in the field of CAR-T cell therapy, such as the bi...

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Detalles Bibliográficos
Autores principales: Ying, Zhitao, He, Ting, Wang, Xiaopei, Zheng, Wen, Lin, Ningjing, Tu, Meifeng, Xie, Yan, Ping, Lingyan, Zhang, Chen, Liu, Weiping, Deng, Lijuan, Wu, Meng, Feng, Feier, Leng, Xin, Du, Tingting, Qi, Feifei, Hu, Xuelian, Ding, Yanping, Lu, Xin-an, Song, Yuqin, Zhu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7908740/
https://www.ncbi.nlm.nih.gov/pubmed/33632155
http://dx.doi.org/10.1186/s12885-021-07934-1