A neutrophil activation signature predicts critical illness and mortality in COVID-19

Pathologic immune hyperactivation is emerging as a key feature of critical illness in COVID-19, but the mechanisms involved remain poorly understood. We carried out proteomic profiling of plasma from cross-sectional and longitudinal cohorts of hospitalized patients with COVID-19 and analyzed clinica...

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Detalles Bibliográficos
Autores principales: Meizlish, Matthew L., Pine, Alexander B., Bishai, Jason D., Goshua, George, Nadelmann, Emily R., Simonov, Michael, Chang, C-Hong, Zhang, Hanming, Shallow, Marcus, Bahel, Parveen, Owusu, Kent, Yamamoto, Yu, Arora, Tanima, Atri, Deepak S., Patel, Amisha, Gbyli, Rana, Kwan, Jennifer, Won, Christine H., Dela Cruz, Charles, Price, Christina, Koff, Jonathan, King, Brett A., Rinder, Henry M., Wilson, F. Perry, Hwa, John, Halene, Stephanie, Damsky, William, van Dijk, David, Lee, Alfred I., Chun, Hyung J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2021
Materias:
Phagocytes, Granulocytes, and Myelopoiesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7908851/
https://www.ncbi.nlm.nih.gov/pubmed/33635335
http://dx.doi.org/10.1182/bloodadvances.2020003568

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7908851/
https://www.ncbi.nlm.nih.gov/pubmed/33635335
http://dx.doi.org/10.1182/bloodadvances.2020003568

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