BRAF V600E mutation as a novel mechanism of acquired resistance to ALK inhibition in ALK-rearranged lung adenocarcinoma: A case report

RATIONALE: Patients with lung adenocarcinoma harboring EML4-ALK rearrangements respond well to multiple ALK tyrosine kinase inhibitors (TKIs). However, the tumor will invariably progress due to acquired resistance. Comprehensive genomic profiling appears to be a promising strategy to reveal the unde...

Descripción completa

Detalles Bibliográficos
Autores principales: Sui, Aixia, Song, Huiling, Li, Yitong, Guo, Litao, Wang, Kai, Yuan, Mingming, Chen, Rongrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
5700
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7909161/
https://www.ncbi.nlm.nih.gov/pubmed/33663128
http://dx.doi.org/10.1097/MD.0000000000024917

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7909161/
https://www.ncbi.nlm.nih.gov/pubmed/33663128
http://dx.doi.org/10.1097/MD.0000000000024917

Ejemplares similares