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Genetic Approach to Elucidate the Role of Cyclophilin D in Traumatic Brain Injury Pathology

Cyclophilin D (CypD) has been shown to play a critical role in mitochondrial permeability transition pore (mPTP) opening and the subsequent cell death cascade. Studies consistently demonstrate that mitochondrial dysfunction, including mitochondrial calcium overload and mPTP opening, is essential to...

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Detalles Bibliográficos
Autores principales: Readnower, Ryan D., Hubbard, William Brad, Kalimon, Olivia J., Geddes, James W., Sullivan, Patrick G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7909250/
https://www.ncbi.nlm.nih.gov/pubmed/33498273
http://dx.doi.org/10.3390/cells10020199