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Genetic Approach to Elucidate the Role of Cyclophilin D in Traumatic Brain Injury Pathology
Cyclophilin D (CypD) has been shown to play a critical role in mitochondrial permeability transition pore (mPTP) opening and the subsequent cell death cascade. Studies consistently demonstrate that mitochondrial dysfunction, including mitochondrial calcium overload and mPTP opening, is essential to...
Autores principales: | Readnower, Ryan D., Hubbard, William Brad, Kalimon, Olivia J., Geddes, James W., Sullivan, Patrick G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7909250/ https://www.ncbi.nlm.nih.gov/pubmed/33498273 http://dx.doi.org/10.3390/cells10020199 |
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