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Novel Flavivirus Attenuation Markers Identified in the Envelope Protein of Alfuy Virus

Alfuy (ALFV) is an attenuated flavivirus related to the Murray Valley encephalitis virus (MVEV). We previously identified markers of attenuation in the envelope (E) protein of the prototype strain (ALFV(3929)), including the hinge region (E273–277) and lack of glycosylation at E154-156. To further d...

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Detalles Bibliográficos
Autores principales: Westlake, Daniel, Bielefeldt-Ohmann, Helle, Prow, Natalie A., Hall, Roy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7909262/
https://www.ncbi.nlm.nih.gov/pubmed/33498300
http://dx.doi.org/10.3390/v13020147