A Continuous Statistical Phasing Framework for the Analysis of Forensic Mitochondrial DNA Mixtures

Despite the benefits of quantitative data generated by massively parallel sequencing, resolving mitotypes from mixtures occurring in certain ratios remains challenging. In this study, a bioinformatic mixture deconvolution method centered on population-based phasing was developed and validated. The m...

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Detalles Bibliográficos
Autores principales: Smart, Utpal, Cihlar, Jennifer Churchill, Mandape, Sammed N., Muenzler, Melissa, King, Jonathan L., Budowle, Bruce, Woerner, August E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7909279/
https://www.ncbi.nlm.nih.gov/pubmed/33498312
http://dx.doi.org/10.3390/genes12020128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7909279/
https://www.ncbi.nlm.nih.gov/pubmed/33498312
http://dx.doi.org/10.3390/genes12020128

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