Lipoprotein Lipase Regulates Microglial Lipid Droplet Accumulation

Microglia become increasingly dysfunctional with aging and contribute to the onset of neurodegenerative disease (NDs) through defective phagocytosis, attenuated cholesterol efflux, and excessive secretion of pro-inflammatory cytokines. Dysfunctional microglia also accumulate lipid droplets (LDs); ho...

Descripción completa

Detalles Bibliográficos
Autores principales: Loving, Bailey A., Tang, Maoping, Neal, Mikaela C., Gorkhali, Sachi, Murphy, Robert, Eckel, Robert H., Bruce, Kimberley D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7909280/
https://www.ncbi.nlm.nih.gov/pubmed/33498265
http://dx.doi.org/10.3390/cells10020198

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7909280/
https://www.ncbi.nlm.nih.gov/pubmed/33498265
http://dx.doi.org/10.3390/cells10020198

Ejemplares similares