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Lipoprotein Lipase Regulates Microglial Lipid Droplet Accumulation
Microglia become increasingly dysfunctional with aging and contribute to the onset of neurodegenerative disease (NDs) through defective phagocytosis, attenuated cholesterol efflux, and excessive secretion of pro-inflammatory cytokines. Dysfunctional microglia also accumulate lipid droplets (LDs); ho...
Autores principales: | Loving, Bailey A., Tang, Maoping, Neal, Mikaela C., Gorkhali, Sachi, Murphy, Robert, Eckel, Robert H., Bruce, Kimberley D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7909280/ https://www.ncbi.nlm.nih.gov/pubmed/33498265 http://dx.doi.org/10.3390/cells10020198 |
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