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Dexamethasone Promotes Aspergillus fumigatus Growth in Macrophages by Triggering M2 Repolarization via Targeting PKM2

Since long-term corticosteroid treatment is associated with emerging opportunistic fungal infections causing high morbidity and mortality in immune-suppressed individuals, here we characterized the impact of dexamethasone (Dex) treatment on Aspergillus fumigatus-related immune modulation. We found b...

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Detalles Bibliográficos
Autores principales: Luvanda, Maureen K., Posch, Wilfried, Vosper, Jonathan, Zaderer, Viktoria, Noureen, Asma, Lass-Flörl, Cornelia, Wilflingseder, Doris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7909285/
https://www.ncbi.nlm.nih.gov/pubmed/33498318
http://dx.doi.org/10.3390/jof7020070