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Droplet Digital PCR Improves IG-/TR-based MRD Risk Definition in Childhood B-cell Precursor Acute Lymphoblastic Leukemia

Minimal residual disease (MRD) is the most powerful prognostic factor in pediatric acute lymphoblastic leukemia (ALL). Real-time quantitative polymerase chain reaction (RQ-PCR) represents the gold standard for molecular MRD assessment and risk-based stratification of front-line treatment. In the pro...

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Detalles Bibliográficos
Autores principales: Della Starza, Irene, Nunes, Vittorio, Lovisa, Federica, Silvestri, Daniela, Cavalli, Marzia, Garofalo, Andrea, Campeggio, Mimma, De Novi, Lucia Anna, Soscia, Roberta, Oggioni, Carlotta, Mussolin, Lara, Biondi, Andrea, Guarini, Anna, Valsecchi, Maria Grazia, Conter, Valentino, Biffi, Alessandra, Basso, Giuseppe, Foà, Robin, Cazzaniga, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7909459/
https://www.ncbi.nlm.nih.gov/pubmed/33655199
http://dx.doi.org/10.1097/HS9.0000000000000543