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Consumption of Oleic Acid on the Preservation of Cognitive Functions in Japanese Elderly Individuals
We recruited 154 community-dwelling elderly individuals and conducted a cohort study to find out the nutrient intake that is suitable for maintaining cognitive function in Japanese elders. Cognitive function was evaluated by the two functional tests, the Montreal Cognitive Assessment (MoCA) and Wech...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7909548/ https://www.ncbi.nlm.nih.gov/pubmed/33498506 http://dx.doi.org/10.3390/nu13020284 |
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author | Sakurai, Keisuke Shen, Chutong Shiraishi, Izumi Inamura, Noriko Hisatsune, Tatsuhiro |
author_facet | Sakurai, Keisuke Shen, Chutong Shiraishi, Izumi Inamura, Noriko Hisatsune, Tatsuhiro |
author_sort | Sakurai, Keisuke |
collection | PubMed |
description | We recruited 154 community-dwelling elderly individuals and conducted a cohort study to find out the nutrient intake that is suitable for maintaining cognitive function in Japanese elders. Cognitive function was evaluated by the two functional tests, the Montreal Cognitive Assessment (MoCA) and Wechsler Memory Scale-Delayed Recall (WMS-DR), and daily nutrient intake was estimated from a Brief-type Self-administered Diet History Questionnaire (BDHQ). By a multiple regression analysis, among the four major nutrients (protein, fat, carbohydrate and ash), we detected a significant correlation between the score of cognitive functions assessed by both MoCA and WMS-DR and daily consumption of fat (p = 0.0317 and p = 0.0111, respectively). Among categories of fatty acid, we found a significant correlation between the score of both MoCA and WMS-DR and consumption of monounsaturated fatty acid (MUFA) (p = 0.0157 and p = 0.0136, respectively). Finally, among MUFAs, we observed a significant correlation between the score of both MoCA and WMS-DR and consumption of oleic acid (p = 0.0405 and p = 0.0165, respectively). From these observations, we can propose that daily consumption of fat, especially in oleic acid, has a beneficial effect against cognitive decline in community-dwelling Japanese elderly individuals. |
format | Online Article Text |
id | pubmed-7909548 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-79095482021-02-27 Consumption of Oleic Acid on the Preservation of Cognitive Functions in Japanese Elderly Individuals Sakurai, Keisuke Shen, Chutong Shiraishi, Izumi Inamura, Noriko Hisatsune, Tatsuhiro Nutrients Article We recruited 154 community-dwelling elderly individuals and conducted a cohort study to find out the nutrient intake that is suitable for maintaining cognitive function in Japanese elders. Cognitive function was evaluated by the two functional tests, the Montreal Cognitive Assessment (MoCA) and Wechsler Memory Scale-Delayed Recall (WMS-DR), and daily nutrient intake was estimated from a Brief-type Self-administered Diet History Questionnaire (BDHQ). By a multiple regression analysis, among the four major nutrients (protein, fat, carbohydrate and ash), we detected a significant correlation between the score of cognitive functions assessed by both MoCA and WMS-DR and daily consumption of fat (p = 0.0317 and p = 0.0111, respectively). Among categories of fatty acid, we found a significant correlation between the score of both MoCA and WMS-DR and consumption of monounsaturated fatty acid (MUFA) (p = 0.0157 and p = 0.0136, respectively). Finally, among MUFAs, we observed a significant correlation between the score of both MoCA and WMS-DR and consumption of oleic acid (p = 0.0405 and p = 0.0165, respectively). From these observations, we can propose that daily consumption of fat, especially in oleic acid, has a beneficial effect against cognitive decline in community-dwelling Japanese elderly individuals. MDPI 2021-01-20 /pmc/articles/PMC7909548/ /pubmed/33498506 http://dx.doi.org/10.3390/nu13020284 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Sakurai, Keisuke Shen, Chutong Shiraishi, Izumi Inamura, Noriko Hisatsune, Tatsuhiro Consumption of Oleic Acid on the Preservation of Cognitive Functions in Japanese Elderly Individuals |
title | Consumption of Oleic Acid on the Preservation of Cognitive Functions in Japanese Elderly Individuals |
title_full | Consumption of Oleic Acid on the Preservation of Cognitive Functions in Japanese Elderly Individuals |
title_fullStr | Consumption of Oleic Acid on the Preservation of Cognitive Functions in Japanese Elderly Individuals |
title_full_unstemmed | Consumption of Oleic Acid on the Preservation of Cognitive Functions in Japanese Elderly Individuals |
title_short | Consumption of Oleic Acid on the Preservation of Cognitive Functions in Japanese Elderly Individuals |
title_sort | consumption of oleic acid on the preservation of cognitive functions in japanese elderly individuals |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7909548/ https://www.ncbi.nlm.nih.gov/pubmed/33498506 http://dx.doi.org/10.3390/nu13020284 |
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