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Population Pharmacokinetics Analysis of Amikacin Initial Dosing Regimen in Elderly Patients

There are limited data of amikacin pharmacokinetics (PK) in the elderly population. Hence, we aimed to describe the population PK of amikacin in elderly patients (>70 years old) and to establish optimized initial dosing regimens. We simulated individual maximum concentrations in plasma (Cmax) and...

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Detalles Bibliográficos
Autores principales: Kato, Hideo, Parker, Suzanne L., Roberts, Jason A., Hagihara, Mao, Asai, Nobuhiro, Yamagishi, Yuka, Paterson, David L., Mikamo, Hiroshige
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7909551/
https://www.ncbi.nlm.nih.gov/pubmed/33498481
http://dx.doi.org/10.3390/antibiotics10020100