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Population Pharmacokinetics Analysis of Amikacin Initial Dosing Regimen in Elderly Patients
There are limited data of amikacin pharmacokinetics (PK) in the elderly population. Hence, we aimed to describe the population PK of amikacin in elderly patients (>70 years old) and to establish optimized initial dosing regimens. We simulated individual maximum concentrations in plasma (Cmax) and...
Autores principales: | Kato, Hideo, Parker, Suzanne L., Roberts, Jason A., Hagihara, Mao, Asai, Nobuhiro, Yamagishi, Yuka, Paterson, David L., Mikamo, Hiroshige |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7909551/ https://www.ncbi.nlm.nih.gov/pubmed/33498481 http://dx.doi.org/10.3390/antibiotics10020100 |
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