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Stabilization of Poly (β-Amino Ester) Nanoparticles for the Efficient Intracellular Delivery of PiggyBac Transposon

The administration of gene-editing tools has been proposed as a promising therapeutic approach for correcting mutations that cause diseases. Gene-editing tools, composed of relatively large plasmid DNA constructs that often need to be co-delivered with a guiding protein, are unable to spontaneously...

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Detalles Bibliográficos
Autores principales: Rodgers, Tina, Muzzio, Nicolas, Watson, Caleb, Romero, Gabriela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7909559/
https://www.ncbi.nlm.nih.gov/pubmed/33498466
http://dx.doi.org/10.3390/bioengineering8020016