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Imd pathway-specific immune assays reveal NF-κB stimulation by viral RNA PAMPs in Aedes aegypti Aag2 cells

BACKGROUND: The mosquito Aedes aegypti is a major vector for the arthropod-borne viruses (arboviruses) chikungunya, dengue, yellow fever and Zika viruses. Vector immune responses pose a major barrier to arboviral transmission, and transgenic insects with altered immunity have been proposed as tools...

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Detalles Bibliográficos
Autores principales: Russell, Tiffany A., Ayaz, Andalus, Davidson, Andrew D., Fernandez-Sesma, Ana, Maringer, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7909628/
https://www.ncbi.nlm.nih.gov/pubmed/33591970
http://dx.doi.org/10.1371/journal.pntd.0008524