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Nucleotide sugar biosynthesis occurs in the glycosomes of procyclic and bloodstream form Trypanosoma brucei

In Trypanosoma brucei, there are fourteen enzymatic biotransformations that collectively convert glucose into five essential nucleotide sugars: UDP-Glc, UDP-Gal, UDP-GlcNAc, GDP-Man and GDP-Fuc. These biotransformations are catalyzed by thirteen discrete enzymes, five of which possess putative perox...

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Detalles Bibliográficos
Autores principales: Sampaio Guther, Maria Lucia, Prescott, Alan R., Kuettel, Sabine, Tinti, Michele, Ferguson, Michael A. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7909634/
https://www.ncbi.nlm.nih.gov/pubmed/33592041
http://dx.doi.org/10.1371/journal.pntd.0009132